NIB researchers publish article in Nature Biotechnology

Biotechnological Hub of the NIB (BTH-NIB)

The purpose of the investment project BTH-NIB is the assurance of the appropriate infrastructural conditions for the use of research and developmental opportunities in the fields of operation of the NIB.

Play Video About project      Publication
  • Official opening of the Biotechnological Hub of the National Institute of Biology and the presentation of the Zei Awards.
    Official opening of the Biotechnological Hub of the National Institute of Biology and the presentation of the Zei Awards.
  • Construction of the Biotechnological Hub of the NIB is complete
    Construction of the Biotechnological Hub of the NIB is complete

Services and products

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  • Agriculture Industry Services

    National Institute of Biology is authorized by the Ministry of Agriculture and the Environment to perform defined tasks of public service for the protection of plants.

 
 
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  • Pharmaceutical and Biotechnology Industry Services

    We offer bioanalytical laboratory support, toxicology studies, genetic toxicology testing of different samples, residual DNA detection, improvements of production lines through systems biology, and cotoxicology studies.

 
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  • Research equipment

    The big research equipment is used as support to our research and educational activities and serves technological development in co-operation with commercial enterprises.

 
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  • Training and Related Services

    We offer hands on training, consulting and technical auditing, development of protocols and workflows, organization of workshops.

 
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  • Mutagenicity analysis under GLP

    On the NIB we have certified GLP laboratory for testing mutagenicity with bacterial reverse mutation assay, or the Ames test (OECD 471).

 

21 Sep
NIB researchers publish article in Nature Biotechnology

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{frontpage}{/frontpage} Recent plant breeding techniques are often using methods of modern biotechnology. The number of different genetically modified crops is increasing and the majority of the plants approved to date carry a trait to increase resistance against insects, viruses or herbicides. Recent plant breeding techniques are often using methods of modern biotechnology. The number of different genetically modified crops is increasing and the majority of the plants approved to date carry a trait to increase resistance against insects, viruses or herbicides. To control the increasing number of different GM organisms, a reliable detection system is crucial for all samples - food, feed, seeds and plants growing in the field.

Analyses are based on detection of inserted DNA and are done in two steps. The sample is first screened for genetic elements which are present in many different GMO. If positive, this is followed by exact identification of  the GMO in the second step.  According to legislation, Joint Research Centre in Ispra is a EU laboratory responsible for validation of the methods we use in this second stage, but there is no organisation obliged to develop and test the methods, that we use in the first stage of analyses. The laboratories therefore need to validate them on their own.

Researchers at NIB institute proposed a system solution to this problem in the August issue of  Nature Biotechnology. They found a case when a detection of GM maize Herculex (TC 1507) was not fully sufficient and proved that suitability od the detection method has to be tracked even when a GMO is on the market for a longer time.

The article can be read at:
http://www.nature.com/nbt/journal/v27/n8/index.html

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