Monitoring of inland waters - SOS/umuC

Biotechnological Hub of the NIB (BTH-NIB)

The purpose of the investment project BTH-NIB is the assurance of the appropriate infrastructural conditions for the use of research and developmental opportunities in the fields of operation of the NIB.

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Monitoring of inland waters - SOS/umuC

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The SOS/umu assay is used to evaluate the ability of testing substance or sample to induce DNA damage. The system is based on alterations in the induction of SOS response as a consequence of DNA damage. SOS/umu assay is convenient as a screening assay for large number of samples as it is a fast and simple method. The test is standardised for the determination of the genotoxic potential of water and wastewater. (ISO/DIS 13829, 2000. Determination of genotoxicity of water and wastewater using the umu-test. TC 147/SC 5.)