Biotechnological Hub of the NIB (BTH-NIB)

The purpose of the investment project BTH-NIB is the assurance of the appropriate infrastructural conditions for the use of research and developmental opportunities in the fields of operation of the NIB.

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Dr. Ana Rotter

Working place: Research Councillor

Telephone number: +386 (0)59 23 28 32
Department: Marine Biology Station Piran


Since March 2014: postdoctoral researcher at the Marine Biology Station. Research area: statistics – time series, network analysis

Since June 2011: postdoctoral researcher at the Department of biotechnology and systems biology. Research area: systems biology, statistics, network analysis, bioinformatics

2005 – May 2011: young researcher on statistics at the National Institute of Biology, Department of biotechnology and systems biology. Doctoral dissertation: »Development and implementation of systems biology tools: a case study of plant physiology data analysis«. Supervisor: prof. dr. Kristina Gruden, co-supervisor prof. dr. Andrej Blejec.

Since 2004: University of Ljubljana, Postgraduate study of statistics

2004 – 2005: employed in fish industry Delamaris d.d., where I worked in the quality control group and later also in the Division for environment and hygene. I implemented and applied environmental testings, monitored the waste water treatment and organized environmental reports as well as monitorings required by law

1996 – 2002: University of Ljubljana, Biotechnical Faculty, interdisciplinary Microbiology programme. Diploma title: »Toxinotypization of Clostridium difficile strains from different countries«. We investigated if different C.difficile toxinotypes occur in different countries and which toxinotypes are prevalent in certain countries. The presence of the binary toxin in different samples was also assessed. Date of defence: 10.10.2002, supervisor: prof. dr. Maja Rupnik

1992 – 1996: Gimnazija Koper

Born April 78.



  • Björn Usadel, Max Planck Golm, Germany. Collaboration was done in 2005 on the field of using bioinformatics with plant gene ontology 
  • Cornelis J. (Ron) van Noorden, AMC (Academisch Medisch Centrum) Amsterdam, the Netherlands on the field of biological interpretation of statistical analysis results – oncology. Collaboration started in 2011 and is still ongoing
ARRS (Slovene research council) projects:
# Code Project name Duration
1 J2-5478 Development and applications of new semantic data mining methods in life sciences 1.8.2013―31.7.2016
EU projects

Cytothreat: Fate and effects of cytostatic pharmaceuticals in the environment and identification of biomarkers for an improved risk assessment on environmental exposure. 

January 2011 – January 2015 

BALMAS: Ballast water management system for Adriatic sea protection.

November 2013 – March 2016

COST network actions: genderSTE: gender, science, technology and environment (

November 2012 – November 2016



  • Biostatistics, experimental design, data analysis, counseling, bioinformatics, network analysis, databases, transcriptomics, MapMan
  • I would like to know and use in practice as many classical statistical tools as possible. Here I mostly use the R, as for its wide usability spectra for statistical analyses but also because of its attractive visualization. I am interested in systems biology. My big ambition is to become a good analyst in the network biology area. 
  • Lately I have become acquainted with the issues regarding gender balance in science. For this reason I visited Norway in the period between September 2013 – October 2013 in order to compare the northern practice with the southern one. In general, there is unfortunately the so-called »sticky floors« and »glass ceilings« for women, who, compared with our male counterparts, climb the carrier ladder more slowly. I would like to inform my colleagues, male and female, about this unequal status.



  • reviewer for Bioinformatics, BMC Bioinformatics, OMICS, Plant Physiology
  • in 2011 I won the national award L'Oreal »For women in science« I am the trade union representative for SVIZ-NIB, covering the rights and duties for around 40 % of NIB personnel.




1. RAMŠAK, Živa, BAEBLER, Špela, ROTTER, Ana, KORBAR, Matej, MOZETIČ, Igor, USADEL, Björn, GRUDEN, Kristina. GoMapMan : integration, consolidation and visualization of plant gene annotations within the MapMan ontology.Nucleic acids research, ISSN 0305-1048, 2013, 9 str, [in press], doi: 10.1093/nar/gkt1056. [COBISS.SI-ID 2966607

2. BUH GAŠPARIČ, Meti, LENASSI, Metka, GOSTINČAR, Cene, ROTTER, Ana, PLEMENITAŠ, Ana, GUNDE-CIMERMAN, Nina, GRUDEN, Kristina, ŽEL, Jana, et al. Insertion of a specific fungal 3'-phosphoadenosine-5'-phosphatase motif into a plant homologue improves halotoleranceand drought tolerance of plants. PloS one, ISSN 1932-6203, Dec. 2013, vol. 8, iss. 12., doi:10.1371/journal.pone.0081872. [COBISS.SI-ID 31021785

3. MOTALN, Helena, GRUDEN, Kristina, HREN, Matjaž, SCHICHOR, Christian, PRIMON, Monika, ROTTER, Ana, LAH TURNŠEK, Tamara. Human mesenchymal stem cells exploit the immune response mediating chemokines to impact the phenotype of glioblastoma. Cell transplantation, ISSN 0963-6897. [Print ed.], 2012, vol. 21, no. 7, str. 1529-1545., doi: 10.3727/096368912X640547. [COBISS.SI-ID 2432079

Link to COBISS, a Slovenian database containing all my publications