NIB

Biotechnological Hub of the NIB (BTH-NIB)

The purpose of the investment project BTH-NIB is the assurance of the appropriate infrastructural conditions for the use of research and developmental opportunities in the fields of operation of the NIB.

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EX_EMPLOYEES

Dr. Matjaž Hren EX_EMPLOYEES

Working place: Research Assistant

Department: Department of Biotechnology and Systems Biology

Education:

  • 2002 - Graduation thesis from the field of biology
  • 2007 - PhD from the field of biotechnology

Employment:

  • 2003 - 2007: young researcher at the Department of Biotechnology and Systems Biology, NIB
  • since 2007: researcher at the same Department

Research areas:

  • secondary metabolite production in plant tissue cultures
  • phytoplasma detection with molecular biology tools (PCR real-time PCR) and development of new detection methods
  • grapevine - phytoplasma interaction
  • cancer therapy research with systems biology tools
  • DNA microarrays
  • bioinformatics, mainly in connection to real-time PCR and DNA-microarray data analysis

Interesting links:

  • International Grape Genome Program
  • Grape Genome Browser
  • The R Project for Statistical Computing
  • Bioconductor
  • Cost 858 Action

Selected bibliography - research papers

  • BAEBLER, Špela, HREN, Matjaž, CAMLOH, Marjana, RAVNIKAR, Maja, BOHANEC, Borut, PLAPER, Igor, UCMAN, Robert, ŽEL, Jana. Establishment of cell suspension cultures of yew (Taxus x media rehd.) and assessment of their genomic stability. In vitro cell. dev. biol., Plant. [Print ed.], 2005, vol. 41, str. 338-343. [COBISS.SI-ID 19226841]
  • HREN, Matjaž, ŽEL, Jana, BAEBLER, Špela, NEMEC, Marjanca, RAVNIKAR, Maja, SCHARA, Milan Valter. Estimating the plasma membrane permeability of Taxus x media cells with the spin probe TEMPOL by EPR. Plant sci. (Limerick). [Print ed.], 2005, vol. 168, str. 535-540. [COBISS.SI-ID 1471567]
  • HREN, Matjaž, BAEBLER, Špela, CAMLOH, Marjana, KOVAČ, Maja, RAVNIKAR, Maja, ŽEL, Jana. Yew (Taxus x media Rehd.) cell suspension cultures as a source of taxanes. Acta physilogiae plantarum, 2006, št. 1, letn. 28, str. 3-8. [COBISS.SI-ID 1563983]
  • HREN, Matjaž, BOBEN, Jana, ROTTER, Ana, KRALJ NOVAK, Petra, GRUDEN, Kristina, RAVNIKAR, Maja. Real-time PCR detection systems for Flavescence dorée and Bois noir phytoplasmas in grapevine : comparision with conventional PCR detection and application in diagnostics. Plant Pathol., 2007, vol. 56, str. 785-796. [COBISS.SI-ID 1773135]
  • HREN, Matjaž, NIKOLIĆ, Petra, ROTTER, Ana, BLEJEC, Andrej, TERRIER, Nancy, RAVNIKAR, Maja, DERMASTIA, Marina, GRUDEN, Kristina. 'Bois noir' phytoplasma induces significant reprogramming of the leaf transcriptome in the field grown grapevine. BMC Genomics, 2009, vol. 10, no. 460, 38 str. http://www.biomedcentral.com/1471-2164/10/460, doi: 10.1186/1471-2164-10-460. [COBISS.SI-ID 2103375]
  • ROTTER, Ana, HREN, Matjaž, BAEBLER, Špela, BLEJEC, Andrej, GRUDEN, Kristina. Finding differentially expressed genes in two-channel DNA microarray datasets: how to increase reliability of data preprocessing. Omics (Larchmt. N.Y.), 2008, vol. 12, no. 3, str. 171-182. http://dx.doi.org/10.1089/omi.2008.0032, doi: doi:10.1089/omi.2008.0032. [COBISS.SI-ID 1888847]
  • ROTTER, Ana, HREN, Matjaž, GRUDEN, Kristina. Gene expression profiling in susceptible interaction of grapevine with its fungal pathogen Eutypa lata : extending MapMan ontology for grapevine. BMC plant biol. (Online), 2009, vol. 9, no. 104, str. 1-14. http://dx.doi.org/10.1186/1471-2229-9-104, doi: 10.1186/1471-2229-9-104. [COBISS.SI-ID 2058319]
  • HREN, Matjaž, RAVNIKAR, Maja, BRZIN, Jernej, ERMACORA, Paolo, CARRARO, Luigi, BIANCO, P.A., CASATI, P., BORGO, M., ANGELINI, E., ROTTER, Ana, GRUDEN, Kristina. Induced expression of sucrose synthase and alcohol dehydrogenase I genes in phytoplasma-infected grapevine plants grown in the field. Plant Pathol., 2009, vol. 58, str. 170-180. , doi: doi:10.1111/j.1365-3059.2008.01904.x. [COBISS.SI-ID 1888335]

Complete bibliography (COBISS)