Proteins of Higher Fungi – from forest to application in Trends in Biotechnology published by NIB and IJS coworkers is one of the TOP 25 articles in the field of Chemical Engineering

Biotechnological Hub of the NIB (BTH-NIB)

The purpose of the investment project BTH-NIB is the assurance of the appropriate infrastructural conditions for the use of research and developmental opportunities in the fields of operation of the NIB.

Play Video About project      Publication
  • Official opening of the Biotechnological Hub of the National Institute of Biology and the presentation of the Zei Awards.
    Official opening of the Biotechnological Hub of the National Institute of Biology and the presentation of the Zei Awards.
  • Construction of the Biotechnological Hub of the NIB is complete
    Construction of the Biotechnological Hub of the NIB is complete

Services and products

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  • Agriculture Industry Services

    National Institute of Biology is authorized by the Ministry of Agriculture and the Environment to perform defined tasks of public service for the protection of plants.

 
 
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  • Pharmaceutical and Biotechnology Industry Services

    We offer bioanalytical laboratory support, toxicology studies, genetic toxicology testing of different samples, residual DNA detection, improvements of production lines through systems biology, and cotoxicology studies.

 
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  • Research equipment

    The big research equipment is used as support to our research and educational activities and serves technological development in co-operation with commercial enterprises.

 
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  • Training and Related Services

    We offer hands on training, consulting and technical auditing, development of protocols and workflows, organization of workshops.

 
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  • Mutagenicity analysis under GLP

    On the NIB we have certified GLP laboratory for testing mutagenicity with bacterial reverse mutation assay, or the Ames test (OECD 471).

 

13 Mar
Proteins of Higher Fungi – from forest to application in Trends in Biotechnology published by NIB and IJS coworkers is one of the TOP 25 articles in the field of Chemical Engineering

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Proteins of Higher Fungi – from forest to application published in Trends in Biotechnology published by NIB and IJS coworkers is one of the TOP 25 articles in the field of Chemical Engineering.

Proteins of Higher Fungi – from forest to application published in Trends in Biotechnology published by NIB and IJS coworkers is one of the TOP 25 articles in the field of Chemical Engineering.

Mushrooms are rapidly becoming recognized as a promising source of novel proteins. Several proteins showing unique features have been isolated, including lectins, lignocellulolytic enzymes, protease inhibitors and hydrophobins. They can offer solutions to several medical and biotechnological problems such as microbial drug resistance, low crop yields, and demands for renewable energy. Large-scale production and industrial application of some fungal proteins proves their biotechnological potential and establishes higher fungi as a valuable, although relatively unexplored, source of unique proteins.


In the past years Researchers at National Institute of Biology, Department of Biotechnology and Systems Biology and Jozef Stefan Institute, Department of Biotechnology have been investigating proteins of higher fungi, their biological activities and biochemical characteristics. Since data on mushroom proteins was relatively scattered, we have prepared a complete overview of the field, emphasizing current and potential applications of mushroom proteins.

Review article "Proteins of higher fungi - from forest to application" has been published in Trends in Biotechnology Journal and provides the first comprehensive overview of known proteins from mushrooms, describes the process of acquiring a new bioactive protein, and provides an overview of current and anticipated applications of these proteins across biotechnology, medicine and agriculture.