VABILO

Nacionalni inštitut za biologijo Vas vabi, da se udeležite seminarja, za izvolitev v znanstveno raziskovalni naziv znanstveni sodelavec:

»Bisfenol A in njegovi analogi: Ali so analogi BPA nevarni za zdravje ljudi?«,

ki ga bo predstavila

dr. Martina Štampar

Seminar bo v sredo, 12. oktobra 2022, ob 15.15.

Potekal bo preko povezave ZOOM.

Povezava:

Povezava: https://us04web.zoom.us/j/79351145245?pwd=Sh75jBoRuhfVC0QaoXUIvsyCus7DfF.1

(Meeting ID: 793 5114 5245; Passcode: 0sQXmi)

Abstract:

»Bisphenols (BPs) are a group of synthetic compounds, among which bisphenol-A (BPA) is the most abundant. They are used as primary raw material for massive production of polymers, especially polycarbonate plastic and epoxy resins and are therefore forming a wide variety of products, from food can linings, infant bottles, toys, receipts and many more, which are used in our everyday life. Early research suggested that BPA had little to no effect in the human body due to its rapid metabolism and thus, low bioavailability. However, in the last two decades data on its adverse health effects are accumulating. The molecular mechanisms proved its strong endocrine-disrupting and genotoxic activity. Due to its hazardous properties, the use of BPA was gradually limited or restricted in the European Union to protect human health and the environment. The ban of BPA in consumer products has prompted the development and increased use of presumably safer BPA analogues. Up to now, more than 200 BPs have been identified as BPA analogues in consumer products (food packaging, toys etc.) and their global industrial production is expected to increase even more in the near future. As a result, various BPs occur in the environment in larger quantities. Despite intensive toxicological research on BPA effects, data for BPA analogues are scarce, while the information on their combined exposure is completely missing. Still, the health risks due to exposures to BPA analogues in general population remain poorly understood. Due to their structural similarity with BPA, the safety of the analogues has been questioned and research data have shown that they possess very similar or even higher endocrine-disrupting and toxic potential as BPA. The majority of BPA analogues are still not regulated and are not included in the legislation although many of them appear to be harmful to humans. While knowledge on the endocrine-disrupting activity of BPA and its analogues is very comprehensive, data on their genotoxic activity are extremely scarce, thus the focus of our research is to study the genotoxic potential of BPA analogues and the mechanisms involved.«

Vljudno vabljeni! Seminar bo potekal v slovenskem jeziku.

Vse, ki boste prisostvovali predavanju, prosimo, da med predavanjem izključite mikrofone.

Dodatne informacije: dr. Martina Štampar, martina.stampar@nib.si.